Study of local protein synthesis in growth cones of embryonic mouse motor neurons
In cultured motoneurons of a mouse model for the motoneuron disease spinal muscular atrophy (SMA), reduced levels of the protein SMN (survival of motoneurons) cause defects in axonal growth. This correlates with reduced β-actin mRNA and protein in growth cones, indicating that anterograde transport...
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| Format: | Doctoral Thesis |
| Language: | English |
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2012
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/6027 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72045 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-72045 https://opus.bibliothek.uni-wuerzburg.de/files/6027/formated_thesis_Reena.pdf |