Identifying the role of Myb-MuvB in gene expression and proliferation of lung cancer cells
The evolutionary conserved Myb-MuvB (MMB) multiprotein complex is a transcriptional master regulator of mitotic gene expression. The MMB subunits B-MYB, FOXM1 as well as target genes of MMB are often overexpressed in different cancer types. Elevated expression of these genes correlates with an advan...
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| Format: | Doctoral Thesis |
| Language: | English |
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2019
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/16181 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-161814 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-161814 https://opus.bibliothek.uni-wuerzburg.de/files/16181/Simon_Katja_MMB_K-RAS_lungcancer.pdf |