Functional analysis of DROSHA and SIX1 mutations in kidney development and Wilms tumor
Wilms tumor (WT) is the most common kidney cancer in childhood. It is a genetically heterogeneous tumor and several genetic alterations have been identified in WT patients. Recurrent mutations were found in the homeo-domain of SIX1 and SIX2 in high proliferative tumors (18.1% of the blastemal-type t...
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Format: | Doctoral Thesis |
Language: | English |
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2019
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/16141 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-161418 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-161418 https://opus.bibliothek.uni-wuerzburg.de/files/16141/Kruber_Philip_%20DROSHA_and_SIX1_mutations.pdf https://opus.bibliothek.uni-wuerzburg.de/files/16141/Supplement.zip |
Internet
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/16141http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-161418
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-161418
https://opus.bibliothek.uni-wuerzburg.de/files/16141/Kruber_Philip_%20DROSHA_and_SIX1_mutations.pdf
https://opus.bibliothek.uni-wuerzburg.de/files/16141/Supplement.zip