Targeting the Bacterial Fatty-Acid Synthesis Pathway: Towards the Development of Slow-Onset Inhibitors and the Characterisation of Protein-Protein Interactions
A continuous arms race between the development of novel antibiotics and the evolution of corresponding resistance mechanisms in bacteria has been observed, since antibiotic agents like arsphenamines (e.g. Salvarsan, developed by Paul Ehrlich [1]), sulphonamides (e.g. Prontosil, Gerhard Domagk [2]) a...
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| Format: | Doctoral Thesis |
| Language: | English |
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2020
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/15664 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-156643 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-156643 https://doi.org/10.25972/OPUS-15664 https://opus.bibliothek.uni-wuerzburg.de/files/15664/Eltschkner_Sandra_Fatty-acid_synthesis_pathway.pdf |