Pathomechanismen von HERG-Ionenkanal-Mutationen als Ursache von menschlichen Repolarisationsstoerungen
Inherited long-QT syndrome is caused by mutations in HERG gene that are associated with distinct mechanisms of ion channel dysfunction (haploinsufficiency or IKr current suppression). Recently, mutations with a gain of HERG channel dysfunction were reported to cause ventricular fibrillation or short...
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| Format: | Doctoral Thesis |
| Language: | German |
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2008
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| Online Access: | https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-2008011414 |