Synthesis, diversification and biomedical applications of 4,5-substitued N-aminoimidazol-2-ones

Synthesis, diversification and biomedical applications of 4,5-substitued N-aminoimidazol-2-ones

In peptide-based medicinal chemistry, mimicry of turn conformations is important because of the significance of such secondary structures for molecular recognition. In this context, N-aminoimidazol-2-one (Nai) residues have demonstrated ability to mimic the central residue of turn conformers. Moreo...

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Bibliographic Details
Main Author: Poupart, Julien
Other Authors: Lubell, William
Language:English
Published: 2021
Subjects:
Réaction de Mannich
N-Aminoimidazolone
Azapeptides
GHRP-6
CD36
Mannich reaction
Vilsmeier formylation
Semicarbazone
Tours-β
β-Turns
Réaction de Vilsemeier
Palladium-catalyzed arylation
Arylation catalysée au palladium
Peptide mimicry
Peptidomimétisme
Chemistry - Organic / Chimie organique (UMI : 0490)
Online Access:http://hdl.handle.net/1866/24770
https://orcid.org/0000-0003-1164-5931

Internet

http://hdl.handle.net/1866/24770
https://orcid.org/0000-0003-1164-5931

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