A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice
L’hypoxie contribue à la guérison cutanée via l’induction de HIF-1 (hypoxia-inducible factor-1). HIF-1 gère l’expression de VEGFA (vascular endothelial growth factor A) en se liant au HRE (hypoxia response element) présent au niveau de son promoteur. Par contre, dans le contexte de la guérison cutan...
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| Language: | en |
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2017
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| Online Access: | http://hdl.handle.net/1866/19161 https://orcid.org/0000-0002-3075-8862 |