Investigating the Contribution of Disordered Domains to the Biological Activity of RNA-binding Proteins

Many proteins contain disordered domains under physiological conditions. These disordered regions may be functional, although under pathological conditions they may lead to protein aggregation and degradation, as observed in proteins related to neurodegenerative diseases. In my thesis study, I aimed...

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Bibliographic Details
Main Author: Tavella, Davide
Format: Others
Published: eScholarship@UMMS 2018
Subjects:
IDP
NMR
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1005
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2014&context=gsbs_diss