Identification of Essential Metabolic and Genetic Adaptations to the Quiescent State in Mycobacterium Tuberculosis: A Dissertation

Mycobacterium tuberculosis stably adapts to respiratory limited environments by entering into a nongrowing but metabolically active state termed quiescence. This state is inherently tolerant to antibiotics due to a reduction in growth and activity of associated biosynthetic pathways. Understanding t...

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Bibliographic Details
Main Author: Rittershaus, Emily S. C.
Format: Others
Published: eScholarship@UMMS 2016
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/876
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1879&context=gsbs_diss