UNDERSTANDING THE CHEMICAL GYMNASTICS OF ENZYME-CATALYZED 1’-1 AND 1’-3 TRITERPENE LINKAGES

UNDERSTANDING THE CHEMICAL GYMNASTICS OF ENZYME-CATALYZED 1’-1 AND 1’-3 TRITERPENE LINKAGES

Squalene synthase (SS) is an essential enzyme in eukaryotic systems responsible for an important branch point in isoprenoid metabolism that leads to sterol formation. The mechanistic complexity of SS has made it a difficult enzyme to study. The green alga Botryococcus braunii race B possesses severa...

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Bibliographic Details
Main Author: Bell, Stephen A
Format: Others
Published: UKnowledge 2014
Subjects:
triterpene synthase
structure-function map
directed evolution
metabolic engineering
green algae
Biochemistry
Biotechnology
Molecular Biology
Molecular genetics
Structural Biology
Online Access:http://uknowledge.uky.edu/pss_etds/43
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1046&context=pss_etds

Internet

http://uknowledge.uky.edu/pss_etds/43
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1046&context=pss_etds

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