PROTEIN KINASE A AND EPAC MEDIATE CHRONIC PAIN AFTER INJURY: PROLONGED INHIBITION BY ENDOGENOUS Y1 RECEPTORS IN DORSAL HORN

Inflammation or nerve injury sensitizes several populations of nociceptive neurons in the dorsal horn of the spinal cord, including those that express the neuropeptide Y (NPY) Y1 receptor (Y1R). Our overall hypothesis is that after tissue or nerve injury, these Y1R-expressing neurons enter a state o...

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Bibliographic Details
Main Author: Fu, Weisi
Format: Others
Published: UKnowledge 2016
Subjects:
NPY
Y1R
AC1
PKA
Online Access:https://uknowledge.uky.edu/physiology_etds/31
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1030&context=physiology_etds