HUMAN RIBOSOMAL RNA GENE CLUSTERS ARE RECOMBINATIONAL HOTSPOTS IN CANCER

The gene that produces the precursor RNA transcript to the three largest ribosomal RNA molecules (rDNA) is present in multiple copies and organized into gene clusters. They represent 0.5% of the diploid human genome but are critical for cellular viability. The individual genes possess very high leve...

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Bibliographic Details
Main Author: Stults, Dawn Michelle
Format: Others
Published: UKnowledge 2009
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_theses/626
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1630&context=gradschool_theses