MODIFICATION OF THE NUCLEOTIDE COFACTOR-BINDING SITE OF CYTOCHROME P450 REDUCTASE TO ENHANCE TURNOVER WITH NADH IN VIVO

NADPH-cytochrome P450 reductase is the electron transfer partner for the cytochromes P450, heme oxygenase, and squalene monooxygenase, and is a component of the nitric oxide synthases and methionine synthase reductase. P450 reductase shows very high selectivity for NADPH and uses NADH only poorly. S...

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Bibliographic Details
Main Author: Elmore, Calvin Lee
Format: Others
Published: UKnowledge 2003
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_diss/467
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1470&context=gradschool_diss