ILLUMINATING DNA PACKAGING IN SPERM CHROMATIN: HOW POLYCATION LENGTHS, UNDERPROTAMINATION AND DISULFIDE LINKAGES ALTERS DNA CONDENSATION AND STABILITY
During spermiogenesis, somatic chromatin is remodeled and a vast majority (> 90%) of DNA histones are replaced by short arginine-rich peptides called protamines. This compaction is immense, with protamine-DNA self-assembly in sperm chromatin resulting in a final volume roughly 1/6th of a somatic...
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| Format: | Others |
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UKnowledge
2019
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| Online Access: | https://uknowledge.uky.edu/chemistry_etds/112 https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1122&context=chemistry_etds |