DOXORUBICIN-INDUCED, TNF-α-MEDIATED BRAIN OXIDATIVE STRESS, NEUROCHEMICAL ALTERATIONS, AND COGNITIVE DECLINE: INSIGHTS INTO MECHANISMS OF CHEMOTHERAPY INDUCED COGNITIVE IMPAIRMENT AND ITS PREVENTION

DOXORUBICIN-INDUCED, TNF-α-MEDIATED BRAIN OXIDATIVE STRESS, NEUROCHEMICAL ALTERATIONS, AND COGNITIVE DECLINE: INSIGHTS INTO MECHANISMS OF CHEMOTHERAPY INDUCED COGNITIVE IMPAIRMENT AND ITS PREVENTION

The works presented in this dissertation provide insights into the mechanisms of chemotherapy-induced cognitive impairment (CICI or “ChemoBrain”) and take steps toward outlining a preventive strategy. CICI is now widely recognized as a complication of cancer chemotherapy experienced by a large perce...

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Bibliographic Details
Main Author: Keeney, Jeriel T
Format: Others
Published: UKnowledge 2013
Subjects:
brain
cognitive impairment
chemotherapy
TNF-alpha
MESNA
Biochemistry
Cognitive Neuroscience
Molecular and Cellular Neuroscience
Oncology
Other Neuroscience and Neurobiology
Online Access:http://uknowledge.uky.edu/chemistry_etds/27
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1032&context=chemistry_etds

Internet

http://uknowledge.uky.edu/chemistry_etds/27
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1032&context=chemistry_etds

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