The Dm-Myb oncoprotein coordinates higher-order chromatin structure to potentiate expression of target genes as well as stabilize facultative heterocrhomatin
Myb is a proto-oncogene that when mutated causes leukemias and lymphomas in birds and mammals. Vertebrates contain three representatives of the Myb gene family consisting of A-, B- and c-Myb, all of which encode DNA-binding factors that are important for the proper expression of genes. Several studi...
Main Author: | Santana, Juan F. |
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Other Authors: | Manak, John R. |
Format: | Others |
Language: | English |
Published: |
University of Iowa
2016
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Subjects: | |
Online Access: | https://ir.uiowa.edu/etd/6270 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7602&context=etd |
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