Inhibition of neutrophil serine proteases by N-arylacyl O-sulfonated aminoglycosides: new therapeutic approach to treat inflammatory lung diseases
Neutrophil serine proteases (NSPs) play an important role in the innate immune system. However, when the balance between NSPs and their endogenous protease inhibitors (PIs) is disrupted, they also play a critical role in the pathogenesis of inflammatory lung disease. Excessive release of NSPs such a...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | English |
| Published: |
University of Iowa
2016
|
| Subjects: | |
| Online Access: | https://ir.uiowa.edu/etd/5447 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6927&context=etd |