Application of modeling-based approaches to study the pharmacokinetics and pharmacodynamics of Delta-9-tetrahydrocannabinol (THC) and its active metabolite

The medical use of marijuana is increasing, yet little is known about the exposure-response relationships resulting in its psychoactive effects. Δ9-tetrahydrocannabinol (THC) and its active metabolite (11-hydroxy-THC; THC-OH) are the principal psychoactive components in marijuana. It is well known t...

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Bibliographic Details
Main Author: Awasthi, Rakesh
Other Authors: Donovan, Maureen D.
Format: Others
Language:English
Published: University of Iowa 2017
Subjects:
Online Access:https://ir.uiowa.edu/etd/5410
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6890&context=etd

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