Systematic analysis of enhancer and promoter interactions

Transcriptional enhancers represent the primary basis for differential gene expression. These elements regulate cell type specificity, development, and evolution, with many human diseases resulting from altered enhancer activity. To date, a key gap in our knowledge is how enhancers select specific p...

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Bibliographic Details
Main Author: He, Bing
Other Authors: Tan, Kai
Format: Others
Language:English
Published: University of Iowa 2015
Subjects:
Online Access:https://ir.uiowa.edu/etd/1972
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6308&context=etd