The Justy mutation disrupts the regulation of gene expression and cell cycle progression during B lymphopoiesis
B lymphopoiesis requires a network of transcription factors that orchestrate changes in gene expression amidst immunoglobulin gene rearrangement and periods of cell proliferation. Although proteins required for the function of this network have been identified, the precise mechanisms that coordinate...
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| Format: | Others |
| Language: | English |
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University of Iowa
2015
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| Online Access: | https://ir.uiowa.edu/etd/1542 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5594&context=etd |