Design, synthesis, and evaluation of small molecule glycosaminoglycan mimics

Glycosaminoglycans (GAGs) are sulfated polysaccharides that mediate a variety of extracellular interactions. Heparan sulfate (HS) is one of the most prominent GAGs on human cell surfaces. Both endogenous proteins, such as growth factors, and exogenous proteins, such as pathogen surface proteins, rec...

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Bibliographic Details
Main Author: Fenner, Amanda Marie
Other Authors: Kerns, Robert J.
Format: Others
Language:English
Published: University of Iowa 2011
Subjects:
Online Access:https://ir.uiowa.edu/etd/4984
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=4984&context=etd