Activators of vinculin enhance cell adhesion and sensitize melanomas to chemotherapy
Metastatic melanoma is among the most aggressive forms of cancer for which there are no effective therapies. Emerging evidence indicates that melanomas can be sensitized to chemotherapy by increasing the function of integrin transmembrane adhesion receptors. Current integrin therapies work by target...
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| Language: | English |
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University of Iowa
2011
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| Online Access: | https://ir.uiowa.edu/etd/2593 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=4722&context=etd |