Focal adhesion kinase signaling regulates highly productive transduction of adeno-associated virus through integrin-mediated endocytosis
Recombinant adeno-associated virus (rAAV) is a widely used gene therapy vector. Although a wide range of rAAV serotypes can effectively enter most cell types, their transduction efficiencies (i.e., transgene expression) can vary widely depending on the target cell...
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| Format: | Others |
| Language: | English |
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University of Iowa
2013
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| Online Access: | https://ir.uiowa.edu/etd/2537 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=4666&context=etd |