Epidermal growth factor receptor inhibitor induces Interleukin-6 via NADPH oxidase enzymes in head and neck cancer cells

The epidermal growth factor receptor (EGFR) is a tyrosine kinase cell surface receptor, belonging to the ErbB family of receptors, which functions to initiate downstream signaling pathways resulting in cellular proliferation, differentiation, migration, adhesion, and metastasis. EGFR is over express...

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Bibliographic Details
Main Author: Fletcher, Elise Virginia May
Other Authors: Burnett-Simons, Andrean
Format: Others
Language:English
Published: University of Iowa 2012
Subjects:
Online Access:https://ir.uiowa.edu/etd/3454
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3455&context=etd