Prostaglandin H synthase catalyzes the oxidation of 4-chlorobiphenyl metabolites, and the in vivo effects on prostaglandin production
Polychlorinated biphenyls (PCBs) exert a broad range of toxicity via both parent compounds and their metabolites. Our previous study showed that hydroquinone (H2Q) metabolites of PCBs act as cosubstrates for prostaglandin H synthase (PGHS), and are oxidized by this enzyme to corresponding quinones (...
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| Format: | Others |
| Language: | English |
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University of Iowa
2011
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| Online Access: | https://ir.uiowa.edu/etd/1101 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2485&context=etd |