Biology of redox active endosomal signaling in response to Il-1-Beta

Interleukin-1-beta (IL-1β) is a potent proinflammatory cytokine. A primary outcome of IL-1β signaling is the activation of NFκB, a transcription factor that induces a large number of immune molecules, apoptotic factors, anti-apoptotic factors, and other transcription factors. Recent work has demonst...

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Bibliographic Details
Main Author: Oakley, Fredrick Daniel
Other Authors: Engelhardt, John F.
Format: Others
Language:English
Published: University of Iowa 2011
Subjects:
Online Access:https://ir.uiowa.edu/etd/1045
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2430&context=etd