Functional genomic analyses of the impact of global hypomethylation and of tumor microenvironment in a rat model of human chondrosarcoma

Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. To achieve a greater understanding of chondrosarcoma tumorigenesis, a model for human chondrosarcoma has been...

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Bibliographic Details
Main Author: Hamm, Christopher Allan
Other Authors: Soares, Marcelo B.
Format: Others
Language:English
Published: University of Iowa 2009
Subjects:
Online Access:https://ir.uiowa.edu/etd/372
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1557&context=etd