Substrate recognition by the yeast Rev1 protein and DNA polymerase ζ

DNA damage blocks replication by classical DNA polymerases, those that replicate nondamaged DNA during normal DNA replication and repair, by altering the geometry of the DNA. Consequently, translesion synthesis, the replication of damaged DNA, is catalyzed by non-classical DNA polymerases, which are...

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Bibliographic Details
Main Author: Howell, Craig A
Other Authors: Washington, M. Todd
Format: Others
Language:English
Published: University of Iowa 2008
Subjects:
Online Access:https://ir.uiowa.edu/etd/7
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1192&context=etd