Substrate recognition by the yeast Rev1 protein and DNA polymerase ζ
DNA damage blocks replication by classical DNA polymerases, those that replicate nondamaged DNA during normal DNA replication and repair, by altering the geometry of the DNA. Consequently, translesion synthesis, the replication of damaged DNA, is catalyzed by non-classical DNA polymerases, which are...
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Format: | Others |
Language: | English |
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University of Iowa
2008
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Online Access: | https://ir.uiowa.edu/etd/7 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1192&context=etd |