High Efficiency Gene Correction in Hematopoietic Cells by Donor Template-free CRISPR/Cas9 Genome Editing
A significant fraction of inherited monogenic disorders are caused by patient-specific mutations dispersed over the entire locus of the affected gene. Although correcting these mutations by introducing healthy gene copies into the genome of the diseased cells proved effective in several clinical gen...
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| Format: | Others |
| Language: | en |
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2018
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| Online Access: | https://tuprints.ulb.tu-darmstadt.de/7247/7/Dissertation_nach_Disputation.pdf Sürün, Duran <http://tuprints.ulb.tu-darmstadt.de/view/person/S=FCr=FCn=3ADuran=3A=3A.html> (2018): High Efficiency Gene Correction in Hematopoietic Cells by Donor Template-free CRISPR/Cas9 Genome Editing.Darmstadt, Technische Universität, [Ph.D. Thesis] |
Internet
https://tuprints.ulb.tu-darmstadt.de/7247/7/Dissertation_nach_Disputation.pdfSürün, Duran <http://tuprints.ulb.tu-darmstadt.de/view/person/S=FCr=FCn=3ADuran=3A=3A.html> (2018): High Efficiency Gene Correction in Hematopoietic Cells by Donor Template-free CRISPR/Cas9 Genome Editing.Darmstadt, Technische Universität, [Ph.D. Thesis]