Etude de la polarité cellulaire et du microenvironnement dans la morphogenèse et les cancers du foie : rôle de la PI3Kδ

Etude de la polarité cellulaire et du microenvironnement dans la morphogenèse et les cancers du foie : rôle de la PI3Kδ

La phosphoinositide 3-kinase p110δ (PI3Kδ) est principalement exprimée dans les cellules hématopoïétiques et son inhibiteur, l'idélalisib est approuvé pour le traitement de la leucémie et du lymphome. Cependant, la fonction de cette isoforme dans les cellules non hématopoïétiques reste insaisis...

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Bibliographic Details
Main Author:	Agnetti, Jean
Other Authors:	Paris Saclay
Language:	fr
Published:	2019
Subjects:	PI3Kδ Polarité Hepatocytes Cellules souches Matrice extracellulaire Hepatoblastome Polarity Stem cells Extracellular matrix Hepatoblastoma
Online Access:	http://www.theses.fr/2019SACLS363

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