Les astrocytes réactifs, des partenaires anti-agrégants dans la maladie de Huntington : identification des mécanismes impliqués dans le dialogue neurone-astrocyte

Les astrocytes réactifs, des partenaires anti-agrégants dans la maladie de Huntington : identification des mécanismes impliqués dans le dialogue neurone-astrocyte

La maladie de Huntington (MH) est une maladie neurodégénérative causée par une extension de répétitions du codon CAG dans le gène de la Huntingtine (Htt). Cette maladie est caractérisée par la mort des neurones striataux et la présence d’agrégats de Htt mutée (mHtt). De plus, au cours de la MH, les...

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Bibliographic Details
Main Author:	Abjean, Laurene
Other Authors:	Université Paris-Saclay (ComUE)
Language:	fr
Published:	2019
Subjects:	Agrégats de huntingtine mutées Maladie de Huntington Astrocytes réactifs Protéostasie Voie JAK2-STAT3 Vecteurs viraux Mutated huntingtin aggregates Huntington's disease Reactive astrocytes Proteostasis Viral vectors JAK2-STAT3 pathway
Online Access:	http://www.theses.fr/2019SACLS088

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