Vers la vectorisation des bisphophonates par les peptides de pénétration cellulaire

Vers la vectorisation des bisphophonates par les peptides de pénétration cellulaire

De nos jours, une des stratégies majeures dans la modulation de la pharmacocinétique des composés bioactifs est leur vectorisation et l’obtention de formes prodrogues. Ce travail est centré sur la vectorisation d’antitumoraux phosphorés à l’aide de peptides favorisant le passage membranaire. Nous av...

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Bibliographic Details
Main Author:	Guedeney, Nicolas
Other Authors:	Sorbonne Paris Cité
Language:	fr
Published:	2018
Subjects:	Cancérologie Peptides de pénétration cellulaire Réaction d’addition de Michael Bisphosphinates Oncology Cell penetrating peptides Michael addition reaction
Online Access:	http://www.theses.fr/2018USPCD024

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