Caractérisation des fonctions génomiques de variants du récepteur des androgènes dans le cancer de la prostate

Caractérisation des fonctions génomiques de variants du récepteur des androgènes dans le cancer de la prostate

Le récepteur des androgènes (RA) est la principale cible thérapeutique du cancer de la prostate (CaP) métastatique. Bien que cette thérapie soit initialement efficace, les effets sont transitoires. De nombreux mécanismes peuvent expliquer la progression du CaP vers un stade de résistance à la castra...

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Bibliographic Details
Main Author:	Ould Madi-Berthelemy, Pauline
Other Authors:	Strasbourg
Language:	fr
Published:	2018
Subjects:	Cancer de la prostate Variants du récepteur des androgènes N-cadhérine Activité transcriptionnelle Liaison à l’ADN Prostate cancer Androgen receptor variants N-cadherin Transcriptional landscape DNA binding 572.8 616.99
Online Access:	http://www.theses.fr/2018STRAJ112

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