Rôle de la sirtuine 1 dans la modulation des réponses apoptotique et autophagique du coeur au stress du réticulum endoplasmique

Rôle de la sirtuine 1 dans la modulation des réponses apoptotique et autophagique du coeur au stress du réticulum endoplasmique

Le réticulum endoplasmique rugueux (RE), assure la synthèse, le repliement et la maturation des protéines de la voie de sécrétion. Les altérations des fonctions physiologiques du RE, entrainent l’accumulation de protéines mal repliées dans la lumière du RE, une condition appelée stress RE. En répons...

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Bibliographic Details
Main Author:	Pires da silva, Julie
Other Authors:	Université Paris-Saclay (ComUE)
Language:	fr
Published:	2018
Subjects:	Stress RE Sirt1 Apoptose Autophagie Réponse UPR Coeur ER Stress Apoptosis Autophagy Upr Heart 570
Online Access:	http://www.theses.fr/2018SACLS211/document

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