Reconstitution du réseau corticostriatal et cible thérapeutique dans la maladie de Huntington

Reconstitution du réseau corticostriatal et cible thérapeutique dans la maladie de Huntington

La maladie de Huntington (MH) est une maladie neurodégénérative avec une transmission dominante, qui entraîne la mort dans les 15 à 20 ans suivant les premiers signes pathologiques. Le gène muté dans la MH contient une répétition de trinucléotide CAG instable qui code pour une expansion de polygluta...

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Bibliographic Details
Main Author:	Virlogeux, Amandine
Other Authors:	Université Paris-Saclay (ComUE)
Language:	fr
Published:	2018
Subjects:	Maladie de Huntington Trafic intracellulaire Cortex Striatum Microfluidique Huntington Disease Intracellular trafficking Microfluidic
Online Access:	http://www.theses.fr/2018SACLS095

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