Spécificité d’attachement sur les glycannes, vers une amélioration des vaccins rotavirus

Spécificité d’attachement sur les glycannes, vers une amélioration des vaccins rotavirus

Les souches humaines de rotavirus du groupe A (RVA) reconnaissent des glycannes fucosylés de la famille des Histo-Blood Group Antigens (HBGAs) et des gangliosides via la protéine de capside VP8*. L’interaction avec les gangliosides est essentielle pour l’entrée cellulaire et l’absence de ligands fuc...

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Bibliographic Details
Main Author:	Barbé, Laure
Other Authors:	Nantes
Language:	fr
Published:	2018
Subjects:	Histo-Blood Group Antigens (HBGAs)
Online Access:	http://www.theses.fr/2018NANT1017/document

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