Recherche des facteurs génétiques contrôlant la réponse à l’infection par Mycobacterium tuberculosis et le développement d’une tuberculose maladie

Recherche des facteurs génétiques contrôlant la réponse à l’infection par Mycobacterium tuberculosis et le développement d’une tuberculose maladie

La tuberculose, causée par Mycobacterium tuberculosis, connaît actuellement une résurgence inquiétante, et l’OMS estime à plus de 10 millions le nombre de nouveaux cas cliniques en 2015 avec environ 1,8 millions de décès dus à la maladie. Environ un tiers de la population mondiale est exposée à M.tu...

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Bibliographic Details
Main Author:	Jabot-Hanin, Fabienne
Other Authors:	Sorbonne Paris Cité
Language:	fr
Published:	2017
Subjects:	Maladie infectieuse Tuberculose Infection tuberculeuse Génétique humaine Épidémiologie génétique IGRA Interféron gamma Quantiféron Liaison génétique Analyse de liaison Étude d’association génétique Analyse d’exomes NGS Variants rares Burden Tests CAST ZXDC BTNL2 Tuberculosis LTBI Pulmonary tuberculosis Human genetics Genetic epidemiology Gamma interferon Quantiferon Genetic linkage Association analysis Exome analysis Rare variants Burden Test 579.374
Online Access:	http://www.theses.fr/2017USPCB253/document

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