Nouvelles cibles pour l'étude et le développement d'outils pharmacologiques originaux pour le traitement des douleurs neuropathiques

Nouvelles cibles pour l'étude et le développement d'outils pharmacologiques originaux pour le traitement des douleurs neuropathiques

Les douleurs neuropathiques désignent une hypersensibilité du système nerveux central sensoriel. C’est une maladie chronique et handicapante qui touche environ 6% de la population française. Cependant, à l’heure actuelle, il n’existe pas de traitement spécifique et efficace. Dans le cadre de cette t...

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Bibliographic Details
Main Author:	Bollenbach, Maud
Other Authors:	Strasbourg
Language:	fr en
Published:	2017
Subjects:	Douleur neuropathique Cytokine pro-inflammatoire TNFα Enzyme PDE5 Kinase MSK1 Relations structure-activité Approche phénotypique Approche moléculaire Hétérocycles Chimie verte Réactions métallocatalysées Neuropathic pain Pro-inflammatory cytokine TNFα PDE5 enzyme MSK1 kinase Structure-activity relationship Phenotypic approach Molecular approach Heterocycles Green chemistry Metalocatalyzed reactions 547.2 615.19
Online Access:	http://www.theses.fr/2017STRAF022

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