Expression tissulaire des gènes paralogues : application au cerveau humain et à son état pathologique

Expression tissulaire des gènes paralogues : application au cerveau humain et à son état pathologique

Dans l’histoire évolutive, deux gènes paralogues sont issus d’un évènement de duplication de leur ancêtre commun. Les gènes paralogues sont caractérisés par des duplications globales de génome (WGD) ou à petite échelle (SSD) et par leur datation. Les WGDs ont lieu à deux reprises à la base de la lig...

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Bibliographic Details
Main Author:	Julien, Solène
Other Authors:	Paris Saclay
Language:	fr
Published:	2017
Subjects:	Gènes paralogues Spécificité tissulaire RNA-Seq Expression cerveau Paralogous genes Tissue-Specificity Brain expression
Online Access:	http://www.theses.fr/2017SACLS545/document

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