Multiscale analysis of poly-ADP-ribosylation dependent chromatin remodeling mechanisms at DNA breaks

Multiscale analysis of poly-ADP-ribosylation dependent chromatin remodeling mechanisms at DNA breaks

Pendant longtemps, la chromatine a été uniquement décrite comme un moyen de compacter près de deux mètres d’ADN dans un noyau de quelques micromètres de diamètre. On sait aujourd’hui que la chromatine représente en fait un élément majeur de régulation de toutes les fonctions nucléaires impliquant l’...

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Bibliographic Details
Main Author:	Lebeaupin, Théo
Other Authors:	Rennes 1
Language:	en
Published:	2017
Subjects:	Chromatine Dommages de l'ADN Décondensation Remodelage PARylation Microscopie à fluorescence Encombrement moléculaire Parp1 H1 Chromatin DNA damage Decondensation Remodeling Fluorescence microscopy Macromolecular crowding
Online Access:	http://www.theses.fr/2017REN1B024/document

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