Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases

Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases

De plus en plus d’inhibiteurs de kinase (IKs) sont testés dans le cancer de la prostate qui représente chez l’homme un enjeu de santé publique majeur de par son incidence (1er cancer) et sa mortalité (4ème cancer). Les essais cliniques pour évaluer l'efficacité des IKs dans cette indication ont...

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Bibliographic Details
Main Author:	Gassiot, Matthieu
Other Authors:	Montpellier
Language:	fr
Published:	2017
Subjects:	Inhibiteurs de kinase Pxr Cancer de la prostate Combinaisons anti-BRAF-Anti-MEK Cyp3a4 Abcb1 Kinase inhibitors Prostate cancer Anti-BRAF-Anti-MEK associations
Online Access:	http://www.theses.fr/2017MONTT133/document

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