Impact de la modulation de TRPM7 et ATF6 sur le cystic fibrosis transmembrane conductance regulator

Impact de la modulation de TRPM7 et ATF6 sur le cystic fibrosis transmembrane conductance regulator

La mucoviscidose est une maladie causée par des mutations du gène cftr entraînant des défauts importants de la protéine CFTR. La mutation la plus fréquente (F508del) est caractérisée par un repliement incorrect conduisant à la rétention de la protéine dans le RE.L’accumulation de CFTR-F508del dans l...

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Bibliographic Details
Main Author:	Huguet, Florentin
Other Authors:	Brest
Language:	fr
Published:	2017
Subjects:	Mucoviscidose CFTR F508del UPR TRPM7 Mg2+ Cystic fibrosis 616.372
Online Access:	http://www.theses.fr/2017BRES0058/document

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