Characterization of Arenaviridae nucleases and design of inhibitors

Characterization of Arenaviridae nucleases and design of inhibitors

Mon projet a porté sur la caractérisation du mécanisme moléculaire des enzymes d'arenavirus (une 3'-5' exoribonucléase et une endonuclease) impliquées dans l'inhibition de la réponse innée IFN de type I et dans le vole de coiffe respectivement, et le développement d'une stra...

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Bibliographic Details
Main Author:	Yekwa, Elsie Laban
Other Authors:	Aix-Marseille
Language:	en
Published:	2017
Subjects:	3'-5' exoribonucléase Endonucléase Immunité innée Développement des inhibiteur Structures cristallographique. 3'-5' exoribonuclease Endonuclease Innate immune evasion Drug-Design X-Ray crystal structure.
Online Access:	http://www.theses.fr/2017AIXM0032

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