Analyse des voies de régulation de la cardiogenèse et de la différenciation cardiomyocytaire

Analyse des voies de régulation de la cardiogenèse et de la différenciation cardiomyocytaire

L'objectif général de ce travail de doctorat a été centré sur l'utilisation des cellules pluripotentes induites humaines dans la modélisation et l'évaluation thérapeutique des pathologies cardiaques. Depuis leur découverte en 2006, les iPSC offrent une opportunité pour le développemen...

Full description

Bibliographic Details
Main Author:	Jeziorowska, Dorota
Other Authors:	Paris 6
Language:	fr en
Published:	2016
Subjects:	IPSC Différenciation Cardiomyocytes Modélisation Edition du génome CRISPRa Differentiation 612.17
Online Access:	http://www.theses.fr/2016PA066631/document

Similar Items

Getting to the heart of cardiovascular evolution in humans
by: Alex Pollen, et al.
Published: (2019-05-01)

A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees
by: Michelle C Ward, et al.
Published: (2019-04-01)

Physiological and pharmacological characteristic of a novel sarcolemmal anionic background conductance (IAB) in heart
by: Borg, John Joseph
Published: (2003)

An investigation of ventricular geometry and architecture using diffusion tensor MRI
by: Gilbert, Stephen Henry
Published: (2008)

Exercise induced cardiac fatigue : insights from novel echocardiographic techniques
by: Oxborough, David L.
Published: (2011)

Changes in the expression of ion channels in the heart during post-natal development
by: Abd Allah, Eman Sayed Hassan
Published: (2008)

Site-specific roles of nitric oxide synthase in cardiac-autonomic signalling
by: Danson, Edward J. F.
Published: (2005)

Metabolic studies in the ageing heart
by: Sample, Jessica
Published: (2006)

Mechano-sensing in cardiac cells
by: Hooper, Charlotte
Published: (2012)

The role of protein kinase B and mitochondrial permeability transition pore in ischaemic preconditioning of myocardium
by: Husainy, Mohammad Ali
Published: (2012)

Identification and characterisation of regulatory elements controlling the expression of the human SERCA2 gene in heart
by: Brady, Marc
Published: (2002)

Mechanoelectric feedback in the right ventricle of a lamb model of tetralogy of fallot
by: Chen, Ruoli
Published: (2003)

Mechanisms regulating mitogen-activated protein kinase phosphatase-2 expression in cardiac myocytes
by: Kodituwakku, Jayanie Subhashi
Published: (2006)

Cardiac and systemic cold tolerance : natural adaptation and clinical application
by: Durrans, Anna
Published: (2004)

Structural and functional coupling of cardiac myocytes and fibroblasts
by: Camelliti, Patrizia
Published: (2005)

The influence of biological mediators on the dynamic function of the aortic root
by: Martin, Misfeld
Published: (2004)

Nonlinear dynamics of cardiovascular aging
by: Shiogai, Yuri
Published: (2007)

Mechanisms regulating expression of the mkp-1 gene in cardiac myocytes
by: Gonzalez Jara, Fabian Rodrigo
Published: (2006)

Examination of pathological changes in the congenitally overloaded morphologically right ventricle
by: McGrath, Casey
Published: (2006)

Computational electromechanics of the mammalian ventricles
by: Benson, Alan Philip
Published: (2006)

Dynamics of cardiac repolarisation
by: Smetana, Peter
Published: (2008)

Microarray analysis of TBX5 and GATA4 transcriptional targets
by: Price, Lynn
Published: (2006)

Characterisation of P2Y receptors expressed in neonatal rat cardiac fibroblasts and their role in a model of ischaemic heart disease
by: Talasila, Amarnath
Published: (2007)

Diurnal variation in post-exercise cardiovascular function
by: Jones, Helen
Published: (2007)

Adenovirally-mediated gene transfer to modify contraction in adult ventricular myocytes
by: Chaudhri, Babar
Published: (2006)

The staircase phenomenon in cardiac muscle
by: Dale, Alison Sarah
Published: (1934)

Ptlysiological right ventricular adaptation in athletes: defining the limits of normality and differentiation from pathology
by: Zaidi, Syed Tatheer Abbas
Published: (2014)

The actomyosin ATPase response to stretch in cardiac muscle
by: Mansfield, Catherine
Published: (2012)

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes
by: Francis Grafton, et al.
Published: (2021-08-01)

Cardiomyocytes Derived from Induced Pluripotent Stem Cells as a Disease Model for Propionic Acidemia
by: Esmeralda Alonso-Barroso, et al.
Published: (2021-01-01)

Leucémie myéloïde chronique : modélisation de l'hématopoïèse leucémique par les cellules souches pluripotentes induites
by: Telliam, Gladys
Published: (2016)

Detection of viral RNA fragments in human iPSC cardiomyocytes following treatment with extracellular vesicles from SARS-CoV-2 coding sequence overexpressing lung epithelial cells
by: Youjeong Kwon, et al.
Published: (2020-11-01)

A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
by: Marcela K. Preininger, et al.
Published: (2016-09-01)

CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes
by: John W. Ostrominski, et al.
Published: (2020-10-01)

Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes
by: Funakoshi, Shunsuke
Published: (2016)

iPSCs and Exosomes: Partners in Crime Fighting Cardiovascular Diseases
by: Giulia Germena, et al.
Published: (2021-06-01)

Comparative Gene Expression Analyses Reveal Distinct Molecular Signatures between Differentially Reprogrammed Cardiomyocytes
by: Yang Zhou, et al.
Published: (2017-09-01)

Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
by: June-Wha Rhee, et al.
Published: (2020-07-01)

Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of β<sub>2</sub>AR-cAMP Signalling
by: Alveera Hasan, et al.
Published: (2020-10-01)

The march of pluripotent stem cells in cardiovascular regenerative medicine
by: Haissam Abou-Saleh, et al.
Published: (2018-07-01)

Cannot write session to /tmp/vufind_sessions/sess_s4r4ehu6kn3q7h9akpc8teesdh