Synthèse et évaluation d'aurones sur des modèles de fibres de tau

Synthèse et évaluation d'aurones sur des modèles de fibres de tau

La fibrillation anormale de la protéine tau est un phénomène présent dans de nombreuses maladies neurodégénératives, dont la maladie d’Alzheimer, et conduit à la formation de fibres amyloïdes appelées dégénérescences neurofibrillaires. L’utilisation de molécules organiques capables de marquer ces fi...

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Bibliographic Details
Main Author:	Lunven, Laurent
Other Authors:	Grenoble Alpes
Language:	fr
Published:	2016
Subjects:	Tau Aurones Alzheimer Fibres amyloïdes Inhibiteur Sonde Amyloid fibres Inhibitor Probe 540
Online Access:	http://www.theses.fr/2016GREAV007/document

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