Amélioration de la solubilité de principes actifs BCS classe 2 par obtention de dispersions solides

Amélioration de la solubilité de principes actifs BCS classe 2 par obtention de dispersions solides

En raison de leur complexité croissante, la solubilité des nouvelles entités chimiques en milieu aqueux est de plus en plus faible. Ainsi, le développement de beaucoup de principes actifs échoue à cause d’une hydrosolubilité insuffisante. De nombreuses technologies existent pour améliorer la solubil...

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Bibliographic Details
Main Author:	Nadaud, Camille
Other Authors:	Ecole nationale des Mines d'Albi-Carmaux
Language:	fr
Published:	2016
Subjects:	Solution solide Dispersion solide Hot melt extrusion Atomisation Amélioration de la solubilité Actif pharmaceutique BCS classe 2 Dispersion technology Solid dispersion Atomization Solubility enhancement Poorly water soluble drug 620
Online Access:	http://www.theses.fr/2016EMAC0001

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