Etude fonctionnelle des variants moléculaires du gène BAG3 associés à la cardiomyopathie dilatée humaine

Etude fonctionnelle des variants moléculaires du gène BAG3 associés à la cardiomyopathie dilatée humaine

Le gène BAG3 a été identifié comme étant un nouveau gène responsable de cardiomyopathie dilatée (CMD), première cause d'insuffisance cardiaque (IC). La protéine BAG3 est une co-chaperonne qui participe au contrôle de l'homéostasie protéique via son rôle dans l'autophagie, protégeant a...

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Bibliographic Details
Main Author:	Korniat, Agathe
Other Authors:	Paris 6
Language:	fr en
Published:	2015
Subjects:	Cardiomyopathie Mutations Bag3 Hsp70 Autophagie Protéostasie Cardiomyopathy BAG3 Autophagy 572.8
Online Access:	http://www.theses.fr/2015PA066716

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