Impact d'une infection virale chronique sur le répertoire T CD8 préimmun : à quel moment perd-on sa naiveté?

Impact d'une infection virale chronique sur le répertoire T CD8 préimmun : à quel moment perd-on sa naiveté?

Le répertoire T CD8 préimmun correspond aux lymphocytes T spécifiques d'antigène circulant en périphérie, et n'ayant pas encore été activés. Ces cellules sont très rares, et de ce fait, n'ont jusqu'ici pas pu être étudiées de façon approfondie. Nous avons dans un premier temps dé...

Full description

Bibliographic Details
Main Author:	Alanio Bréchot, Cécile
Other Authors:	Paris 6
Language:	en
Published:	2015
Subjects:	Répertoire préimmun Lymphocyte T CD8 Signal TCR Immunologie anti-Virale Inflammation chronique Immunité tissulaire T CD8 lymphocytes Preimmune repertoire 571.96
Online Access:	http://www.theses.fr/2015PA066376/document

Similar Items

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients
by: Cécile Alanio, et al.
Published: (2015-11-01)

Identification de nouveaux biomarqueurs permettant la caractérisation des lymphocytes T CD8 mémoires innés
by: Grau, Morgan
Published: (2016)

Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity
by: Jason A. Carter, et al.
Published: (2019-07-01)

Etude du métabolisme énergétique des lymphocytes T CD4+ soumis à une stimulation antigénique chronique
by: Bettonville, Marie
Published: (2016)

Over-Generalizing About GC (Hypoxia): Pitfalls of Limiting Breadth of Experimental Systems and Analyses in Framing Informatics Conclusions
by: Mark R. Boothby, et al.
Published: (2021-05-01)

T-cell receptor Vβ repertoire of CD8<sup>+</sup> T-lymphocyte subpopulations in cutaneous leishmaniasis patients from the state of Rio de Janeiro, Brazil
by: Raquel Ferraz, et al.
Published: (2015-08-01)

CROSS-REACTIVITY OF TCR REPERTOIRE: CURRENT CONCEPTS, CHALLENGES AND IMPLICATION FOR ALLOTRANSPLANTATION
by: Nicolas eDegauque, et al.
Published: (2016-03-01)

Rôle de la protéine Pleckstrin dans la génération de lymphocytes T CD8 mémoires et la mise en place d'une immunité tissulaire
by: Calvez, Mathilde
Published: (2018)

Expression de ZAP-70 dans les lymphocytes B non tumoraux : implications dans la rupture de tolérance et la transformation néoplasique
by: Martin, Mickael
Published: (2018)

Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines
by: Kar-Tong Tan, et al.
Published: (2018-10-01)

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection
by: Sneha Sant, et al.
Published: (2018-06-01)

Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections
by: Magen Ellen Francis, et al.
Published: (2019-01-01)

Étude des distorsions du répertoire immunitaire en tant que facteur pronostique de risque chez les patientes souffrant d’un cancer du sein métastatique en 1ère rechute : étude de la valeur pronostique de la lymphopénie et de la divpénie
by: Manuel, Manuarii
Published: (2012)

Narrowing the gap: preserving repertoire diversity despite clonal selection during the CD4 T cell response
by: Julia eMerkenschlager, et al.
Published: (2015-08-01)

Overview of methodologies for T-cell receptor repertoire analysis
by: Elisa Rosati, et al.
Published: (2017-07-01)

The LCMV gp33-specific memory T cell repertoire narrows with age
by: Bunztman Adam, et al.
Published: (2012-08-01)

The LCMV gp33-specific memory T cell repertoire narrows with age
by: Bunztman, Adam, et al.
Published: (2012)

Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling Pathways
by: Clement Triaille, et al.
Published: (2020-11-01)

Immuno-modulatory functions of tenascin-C in a tumor progression model
by: Murdamoothoo, Devadarssen
Published: (2018)

Mécanismes physiopathologiques des manifestations auto-immunes au cours de la leucémie lymphoïde chronique : rôle de ZAP-70
by: Ghergus, Dana
Published: (2015)

Integrative analysis of CD8 T-cell responses in the context of adaptive immunity to acute Hepatitis C virus infection
by: Wolski, David
Published: (2017)

Importance des glycosaminoglycanes de surface dans les phénomènes inflammatoires liés au cancer
by: Martinez, Pierre
Published: (2014)

Régulation des réponses Th2, induite en début de vie, dans un modèle murin d’inflammation pulmonaire.
by: Dubois, Aurore
Published: (2011)

Coexpresión de CD4 y CD8 en linfocitos de sangre periférica en pacientes positivos para VIH Peripheral blood lymphocyte CD4 and CD8 co-expression in HIV positive patients
by: Alberto Gómez, et al.
Published: (2008-12-01)

T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma
by: Yang Zhang, et al.
Published: (2020-01-01)

Conséquences de l’expression de la synthétase de l’oxyde nitrique de type 2 (NOS2) sur les fonctions des lymphocytes T γδ au cours du développement du mélanome
by: Douguet, Laetitia
Published: (2015)

Characterization of monogenic enteropathies
by: Charbit-Henrion, Fabienne
Published: (2016)

Circulating gluten‐specific, but not CMV‐specific, CD39+ regulatory T cells have an oligoclonal TCR repertoire
by: Laura Cook, et al.
Published: (2020-01-01)

Protection between strains of Papaya ringspot virus: type w in zucchini squash involves competition for viral replication sites Proteção entre estirpes do Papaya ringspot virus: tipo W em abobrinha de moita envolve competição por sítios de replicação viral
by: Débora Maria Sansini Freitas, et al.
Published: (2008-04-01)

Caractérisation de l'infiltrat inflammatoire de l'hépatite chronique du chien
by: Boisclair, Julie
Published: (2016)

Rôle des Interférons de type I dans la régulation de l'expression d'Eomes et l'acquisition d'un phénotype mémoire par les lymphocytes T CD8+
by: Martinet, Valérie
Published: (2018)

The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients
by: Arjun Khunger, et al.
Published: (2019-11-01)

Measuring Intratumoral Heterogeneity of Immune Repertoires
by: Diana Vladimirovna Yuzhakova, et al.
Published: (2020-05-01)

Preparing unbiased T cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling
by: Ilgar Z Mamedov, et al.
Published: (2013-12-01)

Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs
by: Sofya A Kasatskaya, et al.
Published: (2020-12-01)

Les effets synergiques des cytokines pro-inflammatoires et des cytokines impliquées dans l’homéostasie sur les réponses des lymphocytes T CD8 aux antigènes
by: Gagnon, Julien
Published: (2016)

CYTOTOXIC ACTIVITY OF DENDRITIC CELLS AGAINST ACTIVATED CD4+ AND CD8+T-LYMPHOCYTES IN THE CULTURE IN VITRO
by: T. V. Tyrinova, et al.
Published: (2012-05-01)

Intérêt du couple CD5/CD6 dans les lymphocytes B humains
by: Le Dantec, Christelle
Published: (2012)

Dualité fonctionnelle des lymphocytes B dans la tolérance : étude de populations tolérogènes et auto-immunes
by: Gies, Vincent
Published: (2017)

PENINGKATAN SISTEM IMUN OLEH KOMBINASI EKSTRAK ETANOL DAUN AWAR – AWAR (Ficus septica burm. F) DAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) SEBAGAI KO-KEMOTERAPI KANKER PADA TIKUS PUTIH BETINA GALUR SPRAGUE DAWLEY YANG DIINDUKSI DOKSORUBISIN
by: Dewi Indah Sari, et al.
Published: (2015-11-01)