Étude du rôle des facteurs de transcription inducteurs d’EMT dans la mélanomagenèse

Étude du rôle des facteurs de transcription inducteurs d’EMT dans la mélanomagenèse

Les facteurs de transcription inducteurs de la transition épithélio-mésenchymateuse (EMT) sont fréquemment réactivés de manière aberrante dans de nombreux cancers. Dans les carcinomes, ils favorisent dans les étapes précoces le développement tumoral en inhibant les systèmes de sauvegarde tels que la...

Full description

Bibliographic Details
Main Author:	Richard, Geoffrey
Other Authors:	Lyon 1
Language:	fr
Published:	2015
Subjects:	EMT Mélanome ZEB1 Oncogène Plasticité Différenciation Thérapie ciblée Résistance Melanoma Oncogene Plasticity Differentiation Targeted therapy Resistance 616.99
Online Access:	http://www.theses.fr/2015LYO10141/document

Similar Items

GRHL2 Acts as an Anti-Oncogene in Bladder Cancer by Regulating ZEB1 in Epithelial-Mesenchymal Transition (EMT) Process
by: Shen J, et al.
Published: (2020-03-01)

GRHL2 Acts as an Anti-Oncogene in Bladder Cancer by Regulating ZEB1 in Epithelial-Mesenchymal Transition (EMT) Process [Erratum]
by: Shen J, et al.
Published: (2020-10-01)

Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway
by: Xiang Hu, et al.
Published: (2018-03-01)

The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer
by: Rahul Sreekumar, et al.
Published: (2021-08-01)

ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas
by: Lucia Sommerova, et al.
Published: (2020-06-01)

ZEB1 in Pancreatic Cancer
by: Ulrich Wellner, et al.
Published: (2010-08-01)

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance
by: Stanislav Drápela, et al.
Published: (2020-03-01)

MicroRNAs and Their Influence on the ZEB Family: Mechanistic Aspects and Therapeutic Applications in Cancer Therapy
by: Milad Ashrafizadeh, et al.
Published: (2020-07-01)

Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT
by: Qing Li, et al.
Published: (2021-07-01)

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure
by: Marina R. Carpinelli, et al.
Published: (2020-03-01)

Low expression of GATA3 promotes cell proliferation and metastasis in gastric cancer
by: Wei S, et al.
Published: (2017-12-01)

ZEB1 limits adenoviral infectability by transcriptionally repressing the Coxsackie virus and Adenovirus Receptor
by: Lacher Markus D, et al.
Published: (2011-07-01)

Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition
by: Melissa Skibba, et al.
Published: (2017-06-01)

Long Noncoding RNA ZEB1-AS1 Downregulates miR-23a, Promotes Tumor Progression, and Predicts the Survival of Oral Squamous Cell Carcinoma Patients
by: Wang X, et al.
Published: (2021-04-01)

Targeting TRPV1 on cellular plasticity regulated by Ovol 2 and Zeb 1 in hepatocellular carcinoma
by: Chengzhi Xie, et al.
Published: (2019-10-01)

Role of miR-205 in Breast Cancer Development
by: Beldiman, Cornelia
Published: (2014)

miR551b Regulates Colorectal Cancer Progression by Targeting the ZEB1 Signaling Axis
by: Kwang Seock Kim, et al.
Published: (2019-05-01)

Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells
by: Slimane Ait-Si-Ali, et al.
Published: (2013-04-01)

High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival
by: Chao Li, et al.
Published: (2018-12-01)

The roles of ZEB1 in tumorigenic progression and epigenetic modifications
by: Yu Zhang, et al.
Published: (2019-02-01)

Proteomic Analysis of Zeb1 Interactome in Breast Carcinoma Cells
by: Sergey E. Parfenyev, et al.
Published: (2021-05-01)

Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer
by: Hua-Tao Wu, et al.
Published: (2020-02-01)

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition
by: Nicolas Skrypek, et al.
Published: (2018-11-01)

Zeb1, un gen implicat en la repressió transcripcional de l'E-Cadherina durant la transició epiteli-mesènquima. Caracterització del mecanisme de regulació de la seva expressió
by: Guaita Esteruelas, Sandra
Published: (2005)

Clinicopathological significance of ZEB-1 and E-cadherin proteins in patients with oral cavity squamous cell carcinoma
by: Yao X, et al.
Published: (2017-02-01)

Knockdown of lncRNA ZNRD1‐AS1 inhibits progression of bladder cancer by regulating miR‐194 and ZEB1
by: Zhixiang Gao, et al.
Published: (2020-10-01)

ELK3 Mediated by ZEB1 Facilitates the Growth and Metastasis of Pancreatic Carcinoma by Activating the Wnt/β-Catenin Pathway
by: Qiuyan Zhao, et al.
Published: (2021-08-01)

Place des modèles murins dans la compréhension et l'adaptation de la prise en charge thérapeutique du mélanome métastatique
by: Guerreschi, Pierre
Published: (2013)

Targeting ZEB2 By microRNA-129 In Non-Small Cell Lung Cancer Suppresses Cell Proliferation, Invasion And Migration Via Regulating Wnt/β-Catenin Signaling Pathway And Epithelial–Mesenchymal Transition
by: Li X, et al.
Published: (2019-11-01)

Implication de la matrice extracellulaire tumorale dans la transition phénotypique et la résistance aux thérapies ciblées du mélanome
by: Ben Jouira, Rania
Published: (2017)

lncRNA TUG1-Mediated Mir-142-3p Downregulation Contributes to Metastasis and the Epithelial-to-Mesenchymal Transition of Hepatocellular Carcinoma by Targeting ZEB1
by: Chuan He, et al.
Published: (2018-08-01)

The VIM-AS1/miR-655/ZEB1 axis modulates bladder cancer cell metastasis by regulating epithelial–mesenchymal transition
by: Yaoyao Xiong, et al.
Published: (2021-04-01)

Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression
by: He L, et al.
Published: (2020-06-01)

LncRNA SNHG6 is Associated with Poor Prognosis of Gastric Cancer and Promotes Cell Proliferation and EMT through Epigenetically Silencing p27 and Sponging miR-101-3p
by: Kai Yan, et al.
Published: (2017-06-01)

Integrative Transcriptomic Analysis Reveals a Multiphasic Epithelial–Mesenchymal Spectrum in Cancer and Non-tumorigenic Cells
by: Nicholas Panchy, et al.
Published: (2020-01-01)

MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer
by: Cheng Y, et al.
Published: (2019-01-01)

Inhibition of ZEB1-AS1 confers cisplatin sensitivity in breast cancer by promoting microRNA-129-5p-dependent ZEB1 downregulation
by: Jin Gao, et al.
Published: (2020-03-01)

Thérapies ciblées dans le mélanome : mécanismes impliqués dans les effets paradoxaux, les résistances et évaluation de nouvelles combinaisons
by: Boespflug, Amélie
Published: (2018)

Expression of ZEB1-AS1 Expression in Endometrial Carcinoma and Its Correlation with Clinicopathological Features
by: SONG Jiao, et al.
Published: (2020-06-01)

TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition
by: Yoana Dimitrova, et al.
Published: (2017-04-01)

Cannot write session to /tmp/vufind_sessions/sess_j7df2crcgb67c6q83en0vrjeg8