Caractérisation phénotypique, comportementale et neurochimique, de la souris mutante ataxique scrambler (Dab1scm)

Caractérisation phénotypique, comportementale et neurochimique, de la souris mutante ataxique scrambler (Dab1scm)

La souris scrambler (Dab1scm) est un mutant ataxique cérébelleux qui présente une mutation naturelle du gène mdab1, codant pour une protéine intracellulaire nécessaire à la voie de signalisation de la rééline. Cette protéine joue un rôle crucial dans la mise place et la plasticité des structures lam...

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Bibliographic Details
Main Author:	Jacquelin, Cécile
Other Authors:	Université de Lorraine
Language:	fr
Published:	2015
Subjects:	Ataxie cérébelleuse Rééline Comportement sensori-Moteur Ganglions de la base Cerebellar ataxia Reelin Motor behavior Basal ganglia 616.83
Online Access:	http://www.theses.fr/2015LORR0345

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